Father Gift A Part Of Liver To Save His 11 Month Old Daughter With Liver Diseases
Western India’s First Infant undergoes
ABO-incompatible liver transplantation at Global Hospital Mumbai
Baby diagnosis with BILIARY ATRESIA, a chronic
liver disease underwent successful ABO-incompatible
liver transplantation at Global Hospital Mumbai
“Organ donor Shortage, ABO-incompatible
(ABOi) living donor transplantation should be the option to save patient life”:
Doctor
Mumbai: A specialized Paediatric Liver Transplant Team led
by Dr Ravi Mohanka and Dr Anurag Shrimal at Global Hospital, Parel, Mumbai; has performed a medically challenging A-B-O blood
group incompatible (mismatched) liver transplantation in an 11 months baby
(weight 5.5 kg) with end-stage liver disease. It makes this operation as first
successful ABO-incompatible blood transfusion in an infant in western India.
Baby Harshita was diagnosed with biliary atresia. Her liver failed despite
initial surgery. She required liver transplantation urgently. However, due to the absence of a matched donor in her family, liver transplantation looked a distant
dream for her. Due to repeated ICU admissions, finding a donor was a race
against time.
Dr
Ravi Mohanka, Liver Transplant Surgeon at Global Hospital, Parel, Mumbai,
highlighted, “Baby Harshita had
undergone timely Kasai portoenterostomy for biliary atresia. But her illness
progressed. She continued to have jaundice, poor weight gain, fluid in the tummy,
repeated infections requiring ICU admission and blood in the vomitus. The only treatment available was urgent liver transplantation. For any routine liver
transplantation, blood group of donor and recipient should match. However, baby
Harshita did not have a suitable blood group matched donor in her family. With
limited time available and absence of donor, liver transplantation was looking
like an impossible task for Harshita”.
Dr
Vibhor Borkar, Paediatric Hepatologist at Global Hospital, Parel, Mumbai, said, “In ABO-incompatible liver transplantation, we go
ahead with liver transplantation even though blood groups of donor and
recipient do not match. It is a medically challenging task. Such transplantations
have more risk compared to routine transplant. Patients have a higher risk of
rejection and infections. They need stronger immunity suppressing medications
and sometimes specialized dialysis.
Dr
Anurag Shrimal, Paediatric Liver transplant surgeon at Global Hospital, Mumbai,
said, “We had done such operations earlier in
adults. However; for an infant, this was also our first time. Apart from this,
Harshita also had other major challenges like her age was less than 1 year, and
weight only 5.5 kg. Her family understood the need of the situation and risk
involved for such kind of operation. Harshita’s father has B blood group. He
came forward to donate a small part of his liver to her.
The
post-operative recovery of tiny infants is as challenging as the surgery. Keeping
infections at bay was a challenging task in Harshita. She required ICU for only 4
days. She was discharged in 16 days. Now after 2
months of her surgery, she is free of jaundice, active, growing well, gaining milestones
and with no active infections.
Dr Vivek Talaulikar, CEO Global Hospital, Parel,
Mumbai, stated, “A
highly competent liver team is required to perform such a challenging surgery and
managing the baby during the post-operative period. This ABO-incompatible liver
transplantation in Harshita is first such kind surgery done in infants in
western India. The dedicated paediatric liver transplant unit at Global
Hospital provides complete care for all spectrum of liver diseases in children.
Mr Kajrolkar, father of baby Harshita said, “We could see every day Harshita’s condition was deteriorating. When
we learnt that none of us (father and mother) could become a donor for her, we
had lost all our hopes. When we meet Dr Anurag, he explained to us a possibility
of ABO-incompatible transplant. This gave us a ray of hope. We had decided to
scale all the challenges for saving Harshita’s life. Today we find her in good
health, and we are happy about that.
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